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Table 2 The prioritisation model: criteria considered, levels within the criteria, scores and applied weighting coefficients (Coef)

From: DISCONTOOLS: a database to identify research gaps on vaccines, pharmaceuticals and diagnostics for the control of infectious diseases of animals

Criteria

Scores

Coef

Total (score*coef)

Disease knowledge

0

1

2

3

4

2.5

/100

 1. Speed of spread

       

 2. Number of species involved

       

 3. Persistence of infectious agent in the environment

       

 4. Risk of spread to susceptible populations

       

 5. Potential for silent spread

       

 6. Wildlife reservoir and potential spread

       

 7. Vector reservoir and potential spread

       

 8. Variability of the agent

       

 9. Understanding of fundamental immunology

       

 10. Host pathogen interaction

       

Impact on animal health and welfare

0

1

2

3

4

8.33

/100

 1. Disease impact on production

       

 2. Duration of animal welfare impact

       

 3. Proportion of animals affected and suffering pain/injury/distress as a result of the disease

       

Impact on public health – human health

0

1

2

3

4

4.16

/100

 1. Impact of occurrence on human health

       

 2. Likelihood of occurrence

       

 3. Impact of occurrence on food safety

       

 4. Transmissibility (spread from animals to humans)

       

 5. Spread in humans

       

 6. Bioterrorism potential

       

Impact on wider society

0

1

2

3

4

8.33

/100

 1. Economic direct impact (including cumulative cost, e.g. enzootic vs. epizootic)

       

 2. Economic indirect impact (social, market)

       

 3. Agriterrorism potential

       

Impact on trade

0

1

2

3

4

6.25

/100

 1. Impact on international trade due to existing regulations

       

 2. Impact on EC trade due to existing regulations

       

 3. Potential for regionalisation

       

 4. Impact on security of food supply

       

Control tools

+2

+1

0

−1

−2

16.66

/100

 1. Appropriate diagnostics

       

 2. Appropriate vaccines

       

 3. Appropriate pharmaceuticals

       

Total Score